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Sweet 16 - South Region

Betting On The Sweet 16: South Region Odds, Trends, and Picks

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  • The No. 1 seed Baylor Bears have the shortest odds at -150 to win the South Region of the 2021 NCAA Tournament.
  • Villanova is a +240 moneyline underdog against Baylor in their Sweet 16 matchup.
  • The Oral Roberts Golden Eagles +2100 odds are the longest of any team to win the South Region.

INDIANAPOLIS – The 2021 NCAA Men’s Basketball Tournament has had no shortage of upsets as only sixteen teams are left fighting for a chance to be crowned national champion. This year's Sweet 16 features the lowest average seed of all teams in tournament history.

This year’s NCAA Tournament has been the definition of March Madness and the South Region has felt it, as the No. 15 seed Oral Roberts Golden Eagles have made it to the last four teams standing in the South while also being the lowest remaining seed in the tournament.

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Bovada has listed betting odds on the four remaining teams in the South Region. These odds are a great alternative for bettors that want to avoid betting on just a single game.

Odds To Win 2021 NCAA Tournament South Region

  • Baylor (#1)-150
  • Arkansas (#3) +220
  • Villanova (#5) +525
  • Oral Roberts (#15) +2100

Baylor being the favorite to win the South Region is no surprise. Every betting option outside of the Bears -150 odds provides great value should the No. 1 seed fall victim to an upset.

The two Sweet 16 matchups in the South Region give college basketball betting fans various opportunities to beat the bookie.

(1) Baylor Bears vs. (5) Villanova Wildcats Odds @ 5:15 p.m. EST

  • Spread: Baylor (-7.5)
  • Moneyline: Baylor (-290) vs. Villanova (+240)
  • O/U: 140.5

Baylor Betting Trends:

  • The Bears are 1-3 ATS in their last four games.
  • The Over has hit in 12 of Baylor’s last 14 games.

Villanova Betting Trends:

  • Villanova has a 2-1 record ATS in their last three games.
  • The Wildcats are 10-3-1 ATS in their last 14 games as an underdog.

Best Bet: Baylor SU (-290). The Baylor Bears have shown exactly why many have them winning the national championship as their combination of three-point shooting and defense have overwhelmed teams in the first two games. The best for this matchup is to take the Bears SU over Villanova. The Bears had lost three straight games ATS before defeating Wisconsin in the Round of 32 and Villanova is capable of keeping this a one-possession game.

(3) Arkansas Razorbacks vs. (15) Oral Roberts Golden Eagles Odds @ 7:25 p.m. EST

  • Spread: Arkansas (-11.5)
  • Moneyline: Arkansas (-650) vs. Oral Roberts (+425)
  • O/U:159

Arkansas Betting Trends:

  • The total has gone under in four of the Razorbacks' last five games.
  • Arkansas has a 9-1 SU record in their last ten games.

Oral Roberts Betting Trends:

  • Oral Roberts has a 6-0 record ATS in their last six games.
  • The total has gone over in eight of the Golden Eagles' last eleven games.

Best Bet: Oral Roberts ATS (+11.5). The Golden Eagles have been on a historic tear fueled by the nation’s leading scorer Max Abmas. Oral Roberts has the offensive firepower to stick with the Razorbacks and could even pull off the upset and make it to the Elite 8. Arkansas has gotten off to some slow starts in the tournament and Oral Roberts is not a team you want to be trailing behind early. Nonetheless, Arkansas is favored but expect the Golden Eagles to keep this game and cover as they’ve covered the spread in their last six games and have won seven straight games leading up to the Sweet 16.